The First Metabolostasis Conference

July 11-13, 2023 | Online Conference

About the Conference

The First Metabolostasis Conference brought together leading international researchers to explore the emerging field of metabolostasis - the mechanisms that regulate metabolite homeostasis and maintain the delicate balance required for healthy cellular function.

The conference focused on recent discoveries revealing that metabolites, while essential for life, can also form toxic aggregates associated with neurodegenerative diseases such as Alzheimer's and Parkinson's disease. Participants discussed the biological, evolutionary, and medical implications of these findings, fostering interdisciplinary dialogue across chemistry, biology, medicine, and computational sciences.

Scientific Background

Metabolism is the complex network of reactions that enables organisms to generate the energy and molecular building blocks required for life. Although metabolites are essential for cellular function, recent research has shown that they may also form cytotoxic aggregates under certain conditions.

These discoveries have led to the concept of metabolostasis - the quality-control mechanisms that maintain metabolites in a soluble, non-aggregative state while ensuring their continuous availability. Understanding these mechanisms offers new insights into fundamental biology, evolution, and the development of neurodegenerative diseases.

Conference Details

Date July 11-13, 2023

Format Online Conference

Featured Speakers

• Lihi Adler-Abramovich - Tel Aviv University

• Valery Andrushchenko - Czech Academy of Sciences

• Thanh Do - University of Tennessee

• Moran Frenkel-Pinter - Hebrew University of Jerusalem

• Ehud Gazit - Tel Aviv University

• Søren W. Gersting - University Medical Center Hamburg-Eppendorf

• Priyanka Joshi - University of California, Berkeley

• Tuomas Knowles - University of Cambridge

• Dana Laor Bar-Yosef - Tel Aviv University

• Davide Levy - Tel Aviv University

• Daniel Otzen - Aarhus University

• Jana Pilátová - Charles University

• Meital Reches - Hebrew University of Jerusalem

• Peter Roy - University of Toronto

• Daniel Segal - Tel Aviv University

• Orna Staretz-Chacham - Soroka University Medical Center

• Tofail Syed - University of Limerick

• Damien Thompson - University of Limerick

• Loren Williams - Georgia Tech

• Chengqian Yuan - Institute of Process Engineering,

• Einat Zalckvar - Weizmann Institute of Science

Organizing Committee

• Dana Laor

• Tal Yehuda

• Ehud Gazit

Acknowledgment

This conference was made possible through the support of a grant from the John Templeton Foundation.

Event Schedule

Daily Schedule

9:00 AM - 1:00 PM (EDT)

3:00 PM - 7:00 PM (CET)

4:00 PM - 8:00 PM (Israel Time)

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